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小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）基本信息：

Description: Wnt-3a belongs to the Wnt family of signaling proteins that play a key role in maintaining the integrity of embryonic and adult tissues. Expression of Wnt-3a occurs primarily along the dorsal midline across overlapping regions of the Central Nervous System （CNS）. Wnt-3a signaling is essential for various morphogenetic events including embryonic patterning, cell determination, cell proliferation, CNS development, and cytoskeletal formation. like other members of this family, Wnt-3a contains a highly conserved lipid modified cysteine rich domain that is essential for cell signaling. During a biochemical process called the canonical Wnt pathway; Wnt family members bind to and activate seven-pass transmembrane receptors of the Frizzled family ultimay leading to the disruption of β-Catenin degradation. Intracellular accumulation of β-Catenin increases translocation of the protein into the nucleus where it binds to TCF/LEF transcription factors to promote gene expression. Lack of Wnt signaling disrupts transcriptional activation of tumor suppressor genes and has shown to result in neoplastic transformation, oncogenesis, and human degenerative diseases. Recombinant murine Wnt-3a is a monomeric glycoprotein containing 328 amino acid residues. Due to glycosylation, the murine Wnt-3a migrates at an apparent molecular weight of approximay 38.0-41.0 kDa by SDS-PAGE analysis under non-reducing conditions.

Source: cell culture

Molecular Weight: 38-41 kDa Purity: > 75% by SDS-PAGE and HPLC analysis Endotoxin level/內毒素水平: < 0.1 ng per μg of Wnt-3a

Stabilizer: none

Formulation: lyophilized

小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）相關產品：

小鼠wnt-3a蛋白（WNT3A）信號通路（5ug,W3A-M-005）      

小鼠wnt-3a蛋白（WNT3A）信號通路（25ug,W3A-M-025）         

WNT-3a，小鼠wnt蛋白因子（W3A-M-100）,100ug         

WNT-5a，小鼠wnt蛋白因子（W5A-M-005）,5ug    

WNT-5a，小鼠wnt蛋白因子（W5A-M-025）,25ug          

WNT-5a，小鼠wnt蛋白因子（W5A-M-100）,100ug        

小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）應用目的：

小鼠Wnt-3a基因是Wnt基因家族中的重要成員,其編碼表達Wnt-3a信號蛋白.Wnt-3a信號蛋白可以激活經典的Wnt/β-catenin信號通路.Wnt-3a信號蛋白對神經干細胞表現出明顯的促神經元分化的作用.我們應用基因重組的方法,從小鼠胚腦中克隆Wnt-3a cDNA,構建真核表達載體。

小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）英文簡述：

WNT-3a is a member of the WNT family of signaling proteins that play a key role in embryonic development and the integrity of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the beta-catenin pathway. The predicted size of mouse WNT-3a is a monomeric protein containing 333 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 40 kDa by SDS-PAGE analysis under non-reducing conditions.

想更多咨詢小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）,請上海華雅思創(chuàng)生物科技有限公司。上海華雅思創(chuàng)生物科技有限公司是一家專業(yè)為生物科學實驗室研究工作者提供生物試劑，細胞培養(yǎng)基，SFM無血清培養(yǎng)基，抗體，細胞因子，實驗器材，實驗耗材等美國進口的高品質產品，優(yōu)質服務。

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StemRD   MGro-500  MSC medium,chemically-defined,間充質干細胞培養(yǎng)基 500mL/瓶

LONZA   04-418Q    X-VIVO 15 無血清培養(yǎng)基 1L/瓶

Life Technology   087-0112DK    AIM-V? CTS? 無血清細胞培養(yǎng)基（細胞治療級） 1000mL/瓶

Pall   15950-017  Ultroser Serum Substitute 血清替代品 20mL/瓶

LONZA   12-725F   UltraCULTURE Serum-free Medium無血清培養(yǎng)基 500mL/瓶

BD 762165   PAXgene Blood RNA Tube RNA樣本收集管 100管/盒

LONZA 50150   SeaKem? Gold Agarose 金瓊脂糖粉 125g/瓶

LONZA CC-3162   EGM-2 BulletKit( CC-3156 & CC-4176 )套裝 Kit/套

Nunc 159910   175cm2易用培養(yǎng)瓶,PS,已滅菌,瓶蓋:過濾蓋 30個/箱

LONZA LT07-318  MycoAlert? Mycoplasma Detection Kit支原體檢測試劑盒 100Tests/盒

LONZA   LT07-418 MycoAlert? Mycoplasma Detection Kit支原體檢測試劑盒 50Tests/盒

Lonza   50-650U   Kinetic-QCL 192 Test Kit內毒素檢測試劑盒   192T/盒

Corning   431080    175cm⒉細胞培養(yǎng)瓶，Angled頸，透氣蓋 50個/箱

Corning   8388 125mL儲液瓶 Storage Bottles,PS,45mm瓶頸，帶蓋，滅菌，獨立包裝 24個/箱

Corning   430659    2ml凍存管, 聚丙烯，外旋蓋, 可自立圓底 500個/箱

Corning   3290     75cm2 CellBIND Surface培養(yǎng)瓶，已滅菌，透氣蓋 100個/箱

Corning   3292     175cm2 CellBIND Surface培養(yǎng)瓶，已滅菌，透氣蓋 50個/箱

BD-Falcon 352360   Cell Strainer, 100μm, Yellow 100um細胞濾網 50個/箱

BD Falcon 352070 50mL錐形離心管，高透明度聚丙烯,袋裝 500支/箱

BD Falcon 352096 15mL錐形離心管，高透明度聚丙烯,袋裝 500支/箱

BD BioCoat 354234   Matrigel Basement Membrane Matrix(標準型) 10mL/瓶

Cygnus   F550   CHO HCP ELISA Kit,3G宿主蛋白檢測試劑盒 96T/盒

Cygnus   F410   E.coli HCP ELISA Kit 大腸桿菌 96T/盒

Nalgene  5100-0001 Cryo 1℃ Freezing Container梯度降溫凍存盒 1個/箱

Nalgene    5026-0909   CryoBoxes 凍存盒 9X9 陣列，管瓶1.2/2.0mL   24個/箱

Nalgene   2250-0130 50L 可高溫高壓操作的細口大瓶（帶手柄）   1個/箱

Nalgene   2319-0050    20L 可高溫高壓滅菌的細口大瓶（帶放水口）    1個/箱

Hyclone  SH30084.03 FBS 優(yōu)等澳洲胎牛血清 500mL/瓶

PeproTech   100-18B-500   Recombinant Human FGF-basic (154 a.a.)因子 500ug/支

Parafilm PM-996   Parafilm? M Laboratory Film 封口膜 12卷/箱